Overview of Selected Chemical Compounds and Intermediates

Overview of Selected Chemical Compounds and Intermediates

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1. Pharmaceutical Intermediates
Bortezomib Acid Impurity: This is an impurity connected to bortezomib, a proteasome inhibitor Employed in the procedure of various myeloma. Its synthesis or analyze is critical for guaranteeing the purity and basic safety on the drug.
Abiraterone Acetate Intermediate (CAS NO. 122111-01-7): A precursor in the synthesis of abiraterone acetate, a drug Employed in the remedy of prostate most cancers by inhibiting androgen generation.
Imatinib Intermediate (CAS NO. 152460-10-1): A important compound in the synthesis of imatinib, a drug that targets particular forms of cancer, which include Continual myelogenous leukemia (CML).
Docetaxel Intermediate: A compound Employed in the synthesis of docetaxel, a chemotherapy medication that treats a variety of cancers like breast, lung, and prostate most cancers.
two. Chemical Impurities and Byproducts
GeMcitabine Intermediates (T6, T9, eight): These are typically intermediates inside the synthesis of gemcitabine, an anti-most cancers drug. Their research is important for optimizing the production system and making certain higher purity.
Lapatinib Intermediate (CAS NO. 231278-eighty four-five): Lapatinib is utilized to deal with breast most cancers, and these intermediates are associated with its output.
Fulvestrant Intermediates: Fulvestrant is surely an estrogen receptor antagonist Employed in the treatment of breast cancer. A variety of intermediates assist in the synthesis of the drug.
Paclitaxel Aspect Chain Acid (CAS NO. 949023-sixteen-nine): This intermediate is Employed in the synthesis of paclitaxel, a chemotherapy drug productive in managing cancers such as ovarian, breast, and lung Pemetrexed Intermediate cancer.
3. Other Notable Compounds
Irinotecan Hydrochloride Trihydrate (CAS NO. 136572-09-3): A chemotherapy drug Utilized in the procedure of colorectal most cancers and little cell lung cancer.
3-Amino-one-hydroxyadamantane (CAS 702-82-9): This compound is associated with the synthesis of adamantane derivatives, which have different apps, together with antiviral Attributes.
Vildagliptin Intermediates: Employed in the production of vildagliptin, an oral drug for style two diabetes that inhibits the enzyme DPP-4 to regulate blood sugar levels.
4. Miscellaneous Compounds
D-Gluconic Acid δ-Lactone (CAS NO. 61259-forty eight-one): This compound is involved with the synthesis of varied gluconic acid derivatives, which might be used in foodstuff, pharmaceutical, and industrial applications.
Canagliflozin Intermediate two: A precursor in the synthesis of canagliflozin, a medication used to CAS NO. 122111-11-9 deal with type 2 diabetes by inhibiting sodium-glucose co-transporter two (SGLT2).